Multi-nutrient Formulas and Other Substances as Therapies for down Syndrome: an Overview

Theories advocating the supplementation of various vitamins, minerals, amino acids, enzymes, hormones and the drug Piracetam, in various quantities, are sources of considerable controversy within the Down syndrome community. Although vitamin and mineral supplements have been proposed sporadically since the 1940s, little scientific evidence has been accumulated that suggests that their use, or the use of any single ingredient, has any benefit as a general therapy for individuals with Down syndrome. Moreover, research into the general effects of vitamins and minerals in humans, and particularly the long-term effects of supplementation over and above average dietary requirements, is still progressing. An overview of supplementation theories in Down syndrome, and some of the issues that are raised by the advocates of such theories as well as some associated issues is presented.